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Soyselect® features also a standardized content of group-B saponins, that are reported to be biologically active molecules. Soyasaponins are considered important bioactive components
contributing to the beneficial health effects of
soy consumption. Biological effects of especially group-B
soyasaponins have been reported extensively, and include
immunostimulatory, anti-viral, hypocholesterolaemic, hepatoprotective and anticarcinogenic activities (1,2).
Group-B soy saponins aglycone structure
The standardized content of saponins in Soyselect® has been proven able in an animal model to significantly enhance isoflavones bioavailability.
The bioavailability of isoflavones after oral administration of Soyselect® has been evaluated in female rats in comparison with that of a saponin-deprived soy extract (3). The comparison between the AUCs (Area Under Curve) obtained with the administration of 30 mg of isoflavones from Soyselect® with that obtained with 80 mg of isoflavones from the saponin-deprived extract (table 1) shows Soyselect® isoflavones are 1.7 fold more bioavailable.
This result is strongly linked to the presence in Soyselect® of group-B soy saponins.
(1) Rao A.V., Sung M. K., J. Nutr. 125, 717 S (1995).
(2) Kervin S.M., Curr. Med. Chem.-Anti-Cancer Agents 4, 263 (2004).
(3) Soy&Health 2002, London, UK..
